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2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide

Product Name 2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide
Product Code A00005024
Chemical name 2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide
Synonyms 2-Amino-N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-4,5-dimethoxybenzamide;
Impurity
CAS Number 849668-91-3
Alternate CAS #
Molecular form C₂₈H₃₃N₃O₅
Appearance Dark Yellow Solid
Melting Point 85-90°C
Mol. Weight 491.58
Storage Refrigerator
Solubility DMSO (Slightly), Methanol (Slightly)
Stability
Category Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications 2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide is an intermediate in the synthesis of Tariquidar (T007600), a P-glycoprotein drug efflux pump inhibitor that is potentially used in cancer patients.
Dangerous Goods Info
References Fox. E., et al.: Expert. Rev. Anticancer. Ther., 7, 447 (2007); Hernandez, D., et al.: Biochem. Pharmacol., 85, 21 (2013); Bauer, F., et al.: Euro. J. Pharmacol., 696, 18 (2012);
Extra Notes
Documents (MSDS) No Data Available
Keywords Buy 849668-91-3 | Purchase 849668-91-3 | Order 849668-91-3 | 849668-91-3 supplier | 849668-91-3 manufacturer | 849668-91-3 distributor | 849668-91-3 cost
2-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-4,5-dimethoxybenzamide
Product Packings
25mg
100mg
250mg
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